Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
SynKinase
AMG-25
CHF 0.00
In stock
SYN-1125-M0011 mgCHF 270.00
SYN-1125-M0055 mgCHF 702.00
SYN-1125-M01010 mgCHF 1'078.00
SYN-1125-M05050 mgINQ
SYN-1125-M100100 mgINQ
| Product Details | |
|---|---|
| Synonyms | AMG25 |
| Product Type | Chemical |
| Properties | |
| Formula | C23H17N5O2 |
| MW | 395.4 |
| CAS | 1003311-62-3 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: PDGFR | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | IGFSMGCBFTXTJK-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
AMG-25 exhibits potent inhibition of c-Kit with greater than 200-fold selectivity over KDR, p38, Lck and Src.
Product References
- Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-Kit: E. Hu, et al.; J. Med. Chem. 51, 3065 (2008)
Related Products
