Foretinib

CHF 126.00
In stock
SYN-1129-M0011 mgCHF 126.00
SYN-1129-M0055 mgCHF 192.00
SYN-1129-M01010 mgCHF 347.00
SYN-1129-M05050 mgCHF 1'017.00
SYN-1129-M100100 mgCHF 1'700.00
 
More Information
Product Details
Synonyms GSK-1363089; EXEL-2880
Product Type Chemical
Properties
Formula C34H34F2N4O6
MW 632.7
CAS 849217-64-7
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO.
Declaration Manufactured by SynKinase.
Other Product Data Target: VEGFR2 - MET | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key CXQHYVUVSFXTMY-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Foretinib is a novel MET and VEGFR2 kinase inhibitor with IC(50) values of 0.4 and 0.8nM for MET and VEGFR2 respectively.
Product References
  1. Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis: M. Zillhardt, et al.; Clin. Cancer Res. 17, 4042 (2011)
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