SYN-1130-M0011 mgCHF 270.00
SYN-1130-M0055 mgCHF 688.00
SYN-1130-M01010 mgCHF 986.00
|Solubility||Soluble in DMSO.|
|Declaration||Manufactured by SynKinase.|
|Other Product Data||
Target: TYK2 | Kinase Group: RTK | Substrate: Tyrosine
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
Bayer-18 is a selective TYK2 inhibitor, with an IC(50) of 18.7nM on TYK2 as measured by TYK2 HTRF assays. The compound shows 1000 fold selectivity against JAK2, CDK and KDR kinases in similar HTRF assays.
- New phenyl-pyrimidin-2-yl-amine compounds are tyrosine kinase 2 inhibitors useful for treating E.G. rheumatoid arthritis, Crohn's disease, asthma, multiple sclerosis, adult respiratory distress syndrome, allergic alveolitis and uveitis: B. Buchmann, et al.; DE102009015070 (2010)