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SynKinase
BMS-599626
CHF 0.00
In stock
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| Product Details | |
|---|---|
| Synonyms | AC-480; BMS599626 |
| Product Type | Chemical |
| Properties | |
| Formula | C27H27FN8O3 |
| MW | 530.6 |
| CAS | 714971-09-2 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: EGFR - HER2 | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | LUJZZYWHBDHDQX-QFIPXVFZSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
BMS-599626 is an orally bioavailable, highly selective and potent pan-HER kinase inhibitor. It inhibits HER1 and HER2 with IC(50) values of 20 and 30nM, respectively.
Product References
- Preclinical antitumor activity of BMS-599626, a pan-HER kinase inhibitor that inhibits HER1/HER2 homodimer and heterodimer signaling: T.W. Wong, et al.; Clin. Cancer Res. 12, 6186 (2006)
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