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SynKinase
TAK-285
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| Product Details | |
|---|---|
| Synonyms | TAK285 |
| Product Type | Chemical |
| Properties | |
| Formula | C26H25ClF3N5O3 |
| MW | 548.0 |
| CAS | 871026-44-7 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: EGFR - HER2 | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | ZYQXEVJIFYIBHZ-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
TAK-285 is a novel investigational dual HER2/EGFR inhibitor with IC(50) values of 17 and 23nM, respectively.
Product References
- Design and synthesis of novel human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors bearing a pyrrolo[3,2-d]pyrimidine scaffold: T. Ishikawa, et al.; J. Med. Chem. 54, 8030 (2011)
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