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SynKinase
NIBR-17
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Product Details | |
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Synonyms | NIBR17 |
Product Type | Chemical |
Properties | |
Formula | C18H20N8O2 |
MW | 380.4 |
CAS | 944396-88-7 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | XZTYTIOLZIKUJR-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS |
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Product Specification Sheet | |
Datasheet |
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Description
NIBR-17 is a pan class I PI3K inhibitor with IC(50) values of 1, 9.2, 9 and 20nM, respectively for PI3Kα - δ.
Product References
- Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors: M.T. Burger, et al.; ACS Med. Chem. Lett. 2, 34 (2010)