SynKinase

NIBR-17

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Product Details
Synonyms	NIBR17
Product Type	Chemical
Properties
Formula	C₁₈H₂₀N₈O₂
MW	380.4
CAS	944396-88-7
Purity Chemicals	≥95%
Appearance	Solid.
Solubility	Soluble in DMSO.
Declaration	Manufactured by SynKinase.
Other Product Data	Target: PI3K \| Kinase Group: Lipid Kinase \| Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	XZTYTIOLZIKUJR-UHFFFAOYSA-N
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

NIBR-17 is a pan class I PI3K inhibitor with IC(50) values of 1, 9.2, 9 and 20nM, respectively for PI3Kα - δ.

Product References

Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors: M.T. Burger, et al.; ACS Med. Chem. Lett. 2, 34 (2010)

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