SynKinase

GNE-477

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SYN-1148-M0011 mgCHF 277.00
SYN-1148-M0055 mgCHF 546.00
SYN-1148-M01010 mgCHF 766.00
SYN-1148-M05050 mgINQ
SYN-1148-M100100 mgINQ
 
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Product Details
Synonyms GNE477
Product Type Chemical
Properties
Formula C21H28N8O3S2
MW 504.6
CAS 1032754-81-6
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO.
Declaration Manufactured by SynKinase.
Other Product Data Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key AKKCGLXULFRAET-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
GNE 477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC(50) value of 4nM and 21nM respectively.
Product References
  1. Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor: T.P. Heffron, et al.; Bioorg. Med. Chem. Lett. 20, 2408 (2010)
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