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SYN-1150-M0011 mgCHF 142.00
SYN-1150-M0055 mgCHF 213.00
SYN-1150-M01010 mgCHF 355.00
SYN-1150-M05050 mgCHF 1'064.00
SYN-1150-M100100 mgINQ
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Product Details
Synonyms GDC-0980
Product Type Chemical
Formula C23H30N8O3S
MW 498.6
CAS 1032754-93-0
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
GDC-0980 (RG7422) is a selective, dual PI3 Kinase and mTOR Kinase inhibitor with IC(50) values of 5, 27, 7, and 14nM for PI3Kα-δ respectively. It inhibits mTOR with a Ki of 17nM.
Product References
  1. Discovery of a potent, selective, and orally available class I phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) kinase inhibitor (GDC-0980) for the treatment of cancer: D.P. Sutherlin, et al.; J. Med. Chem. 54, 7579 (2011)
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