CEP-33779

CHF 174.00
In stock
SYN-1156-M0011 mgCHF 174.00
SYN-1156-M0055 mgCHF 287.00
SYN-1156-M01010 mgCHF 461.00
SYN-1156-M05050 mgCHF 1'514.00
SYN-1156-M100100 mgCHF 2'304.00
 
More Information
Product Details
Synonyms CEP33779
Product Type Chemical
Properties
Formula C24H26N6O2S
MW 462.6
CAS 1346168-57-7
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: JAK | Kinase Group: PTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key RFZKSQIFOZZIAQ-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
CEP-33779 is a highly selective, orally active inhibitor for JAK2 with an IC(50) of 1.8nM in enzyme and 61nM in cell activity. It inhibits JAK3 with an IC(50) of 150nM.
Product References
  1. A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis: K.L. Stump, et al.; Arthritis Res. Ther. 13, R68 (2011)
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