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SynKinase
TAE684
CHF 0.00
In stock
SYN-1159-M0011 mgCHF 128.00
SYN-1159-M0055 mgCHF 227.00
SYN-1159-M01010 mgCHF 355.00
SYN-1159-M05050 mgCHF 1'050.00
SYN-1159-M100100 mgINQ
Product Details | |
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Synonyms | NVP-TAE684 |
Product Type | Chemical |
Properties | |
Formula | C30H40ClN7O3S |
MW | 614.2 |
CAS | 761439-42-3 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO or ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: ALK | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | QQWUGDVOUVUTOY-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
TAE684 is a potent and selective ALK inhibitor with an IC(50) of 3nM. It is 100-fold more sensitive for ALK over InsR.
Product References
- Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK: A.V. Galkin, et al.; PNAS 104, 270 (2007)