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SynKinase
TAE684
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| Product Details | |
|---|---|
| Synonyms | NVP-TAE684 |
| Product Type | Chemical |
| Properties | |
| Formula | C30H40ClN7O3S |
| MW | 614.2 |
| CAS | 761439-42-3 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: ALK | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | QQWUGDVOUVUTOY-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
TAE684 is a potent and selective ALK inhibitor with an IC(50) of 3nM. It is 100-fold more sensitive for ALK over InsR.
Product References
- Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK: A.V. Galkin, et al.; PNAS 104, 270 (2007)
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