LDK378

CHF 72.00
In stock
SYN-1199-M0011 mgCHF 72.00
SYN-1199-M0055 mgCHF 108.00
SYN-1199-M01010 mgCHF 144.00
SYN-1199-M05050 mgCHF 467.00
SYN-1199-M100100 mgCHF 778.00
 
More Information
Product Details
Synonyms LDK-378
Product Type Chemical
Properties
Formula C28H36ClN5O3S
MW 558.1
CAS 1032900-25-6
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO (heat) or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: ALK | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key VERWOWGGCGHDQE-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
LDK378 is potent inhibitor against ALK with IC(50) of 0.2nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
Product References
  1. Targeting Anaplastic Lymphoma Kinase in Lung Cancer: A.T. Shaw & B. Solomon; Clin. Cancer Res. 17, 2081 (2011)
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