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SynKinase
LDK378
85
CHF
CHF 85.00
In stock
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| Product Details | |
|---|---|
| Synonyms | LDK-378 |
| Product Type | Chemical |
| Properties | |
| Formula | C28H36ClN5O3S |
| MW | 558.1 |
| CAS | 1032900-25-6 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO (heat) or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: ALK | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | VERWOWGGCGHDQE-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
LDK378 is potent inhibitor against ALK with IC(50) of 0.2nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
Product References
- Targeting Anaplastic Lymphoma Kinase in Lung Cancer: A.T. Shaw & B. Solomon; Clin. Cancer Res. 17, 2081 (2011)
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