SYN-1168-M0011 mgCHF 277.00
SYN-1168-M0055 mgCHF 546.00
SYN-1168-M01010 mgCHF 858.00
|Solubility||Soluble in DMSO.|
|Declaration||Manufactured by SynKinase.|
|Other Product Data||
Target: B-RAF - VEGFR2 | Kinase Group: TKL | Substrate: Serine-Threonine
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
Takeda-6d has potent inhibitory activity in both B-RAF with an IC(50) of 7.0nM and VEGFR2 with an IC(50) of 2.2nM.
- Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds: M. Okaniwa, et al.; J. Med. Chem. 55, 3452 (2012)