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SynKinase
SCH900776
CHF 0.00
In stock
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| Product Details | |
|---|---|
| Synonyms | MK-8776 |
| Product Type | Chemical |
| Properties | |
| Formula | C15H18BrN7 |
| MW | 376.3 |
| CAS | 891494-63-6 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: Chk1 - Chk2 | Kinase Group: CAMK | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | GMIZZEXBPRLVIV-SECBINFHSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
SCH900776 is a selective Chk1 inhibitor with an IC(50) of 3nM. It shows 50-fold selectivity for Chk1 versus Chk2.
Product References
- Preclinical development of the novel Chk1 inhibitor SCH900776 in combination with DNA-damaging agents and antimetabolites: R. Montano, et al.; Mol. Cancer Ther. 11, 427 (2012)
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