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SynKinase
Bafetinib
CHF 0.00
In stock
SYN-1179-M0011 mgCHF 142.00
SYN-1179-M0055 mgCHF 241.00
SYN-1179-M01010 mgCHF 440.00
SYN-1179-M05050 mgCHF 1'334.00
SYN-1179-M100100 mgINQ
Product Details | |
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Synonyms | NS-187; INNO-406 |
Product Type | Chemical |
Properties | |
Formula | C30H31F3N8O |
MW | 576.6 |
CAS | 859212-16-1 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: BCR | Kinase Group: PTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | ZGBAJMQHJDFTQJ-DEOSSOPVSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl, Lyn inhibitor with IC(50) values of 5.8nM and 19nM, respectively.
Product References
- NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia: S. Kimura, et al.; Blood 106, 3948 (2005)