Bafetinib

CHF 120.00
In stock
SYN-1179-M0011 mgCHF 120.00
SYN-1179-M0055 mgCHF 203.00
SYN-1179-M01010 mgCHF 371.00
SYN-1179-M05050 mgCHF 1'125.00
SYN-1179-M100100 mgCHF 1'700.00
 
More Information
Product Details
Synonyms NS-187; INNO-406
Product Type Chemical
Properties
Formula C30H31F3N8O
MW 576.6
CAS 859212-16-1
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: BCR | Kinase Group: PTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key ZGBAJMQHJDFTQJ-DEOSSOPVSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl, Lyn inhibitor with IC(50) values of 5.8nM and 19nM, respectively.
Product References
  1. NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia: S. Kimura, et al.; Blood 106, 3948 (2005)
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