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SynKinase
LY2784544
CHF 0.00
In stock
SYN-1196-M0011 mgCHF 128.00
SYN-1196-M0055 mgCHF 227.00
SYN-1196-M01010 mgCHF 355.00
SYN-1196-M05050 mgCHF 1'263.00
SYN-1196-M100100 mgINQ
| Product Details | |
|---|---|
| Synonyms | LY-2784544 |
| Product Type | Chemical |
| Properties | |
| Formula | C23H25ClFN7O |
| MW | 469.9 |
| CAS | 1229236-86-5 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: JAK2 | Kinase Group: PTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | SQSZANZGUXWJEA-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Product References
- Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F: L. Ma, et al.; Blood Cancer J. 3, e109 (2013)
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