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AdipoGen Life Sciences
Vaspin (human) (rec.)
130
CHF
CHF 130.00
In stock
AG-40A-0064Y-C01010 µgCHF 130.00
AG-40A-0064Y-30103 x 10 µgCHF 265.00
| Product Details | |
|---|---|
| Synonyms | Visceral Adipose Tissue-derived Serine Protease Inhibitor; Serpin A12; OL-64 |
| Product Type | Protein |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence |
Human vaspin (aa 21-414) is fused at the N-terminus to a FLAG®-tag. |
| Crossreactivity | Human |
| MW | ~55kDa (SDS-PAGE) |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.01EU/μg purified protein (LAL test; Lonza). |
| Concentration | 0.1mg/ml after reconstitution. |
| Reconstitution | Reconstitute with 100μl sterile water. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data |
UniProt link Q8IW75: Vaspin (human) FLAG is a registered trademark of Sigma-Aldrich Co. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Use/Stability |
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Vaspin (Visceral adipose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters. Vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.
Product References
- A fluorescent lateral flow biosensor for the quantitative detection of Vaspin using upconverting nanoparticles: A. Mushin, et al.; Spectrochim. Acta A Mol. Biomol. Spectrosc. 226, 117610 (2019)
- Aptamer duo-based portable electrochemical biosensors for early diagnosis of periodontal disease: C. Joe, et al.; Biosensors Bioelectronics 199, 113884 (2022)
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