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AdipoGen Life Sciences
Nocardamine
150
CHF
CHF 150.00
In stock
AG-CN2-0150-M0011 mgCHF 150.00
AG-CN2-0150-M0055 mgCHF 660.00
| Product Details | |
|---|---|
| Synonyms | Deferrioxamine E; Desferrioxamine E |
| Product Type | Chemical |
| Properties | |
| Formula |
C27H48N6O9 |
| MW | 600.7 |
| CAS | 26605-16-3 |
| Source/Host Chemicals | Isolated from Streptomyces sp. K04-0144. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | White to off-white solid. |
| Solubility | Soluble in DMSO, methanol, ethanol or water. |
| InChi Key | NHKCCADZVLTPPO-UHFFFAOYSA-N |
| Smiles | ON1CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC1=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic [1, 6].
- Anti-mycobacterial [7].
- Siderophore (iron (Fe) chelating compound) [5, 8].
- Inducer of morphological changes in insect cells [3].
- Antioxidant [4].
- Anticancer compound [2, 8].
Product References
- The description and antibiotic production of Streptomyces hygroscopicus var. geldanus: C. DeBoer & A. Dietz; J. Antibiot. 29, 1182 (1976)
- Neuroblastoma sensitivity to growth inhibition by deferrioxamine: evidence for a block in G1 phase of the cell cycle: C. Brodie, et al.; Cancer Res. 53, 3968 (1993)
- Morphological changes in insect BM-N4 cells induced by nocardamine: K. Matsubara, et al.; Biosci. Biotechnol. Biochem. 62, 2049 (1998)
- Antioxidant properties of desferrioxamine E, a new hydroxamate antioxidant: E. Shimoni, et al.; J. Am. Oil Chem. Soc. 75, 1453 (1998)
- A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases: G.L. Challis; ChemBioChem 6, 601 (2005)
- Desferrioxamine E produced by Streptomyces griseus stimulates growth and development of Streptomyces tanashiensis: K. Yamanaka, et al.; Microbiology 151, 2899 (2005)
- Cyclic peptides of the nocardamine class from a marine-derived bacterium of the genus Streptomyces: H.S. Lee, et al.; J. Nat. Prod. 68, 623 (2005)
- Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activity: N.I. Kalinovskaya, et al.; Microbiol. Res. 166, 654 (2011)
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