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AdipoGen Life Sciences
NG 012
130
CHF
CHF 130.00
In stock
AG-CN2-0155-M0011 mgCHF 130.00
AG-CN2-0155-M0055 mgCHF 520.00
| Product Details | |
|---|---|
| Synonyms | BK223A; 15G256α; 32-Hydroxy-orbuticin |
| Product Type | Chemical |
| Properties | |
| Formula |
C32H38O15 |
| MW | 662.7 |
| CAS | 141731-76-2 |
| Source/Host Chemicals | Isolated from Penicillium sp. FKI-5387. |
| Purity Chemicals | ≥95% (TLC) |
| Appearance | Pale white solid. |
| Solubility | Soluble in methanol, ethanol, ethyl acetate, chloroform, acetonitrile or acetone. Insoluble in water or hexane. |
| InChi Key | QFILNQIVBJLREP-RZOYPLJHSA-N |
| Smiles | C[C@@H]1CC2=C(C(O)=CC(O)=C2)C(=O)O[C@H](C)CC(=O)O[C@H](CO)CC(=O)O[C@H](C)CC2=C(C(O)=CC(O)=C2)C(=O)O[C@H](C)CC(=O)O1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic. Mycotoxin. Very weak cytotoxic activity.
- Antifungal. Inhibits cell wall biosynthesis.
- Nerve growth factor (NGF) potentiator.
Product References
- NG 011 and NG 012, novel potentiators of nerve growth factor. I. Taxonomy, isolation, and physico-chemical and biological properties: M. Ito, et al.; J. Antibiot. 45, 1559 (1992)
- NG 011 and NG 012, novel potentiators of nerve growth factor. II. The structure determination of NG-011 and NG-012: M. Ito, et al.; J. Antibiot. 45, 1566 (1992)
- Antifungal macrocyclic polylactones from Penicillium verruculosum: J. Breinholt, et al.; J. Antibiot. 46, 1101 (1993)
- Isolation and identification of antifungal polyesters from the marine fungus Hypoxylon oceanicum LL-15G256: G. Schlingmann, et al.; Tetrahedron 58, 6825 (2002)
- Biomimetic Synthesis of Resorcylate Natural Products Utilizing Late Stage Aromatization: Concise Total Syntheses of the Marine Antifungal Agents 15G256ι and 15G256β: I. Navarro, et al.; JACS 130, 10293 (2008)
- New Cytotoxic Metabolites from the Marine-Derived Fungus Penicillium sp. ZLN29: H. Gao, et al.; Helv. Chim. Acta 96, 514 (2013)
- New polyesters from Talaromyces flavus: J.-W. He, et al.; Tetrahedr. 70, 4425 (2014)
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