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AdipoGen Life Sciences
Macrosphelide A
170
CHF
CHF 170.00
In stock
AG-CN2-0152-M0011 mgCHF 170.00
AG-CN2-0152-M0055 mgCHF 680.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C16H22O8 |
| MW | 342.4 |
| CAS | 172923-77-2 |
| Source/Host Chemicals | Isolated from Paraconiothyrium sporulosum FO-5050. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | White solid. |
| Solubility | Soluble in methanol, DMSO, chloroform, ethyl acetate or dimethyl ether. Insoluble in water or hexane. |
| InChi Key | MJMMUATWVTYSFD-MGQLGLDKSA-N |
| Smiles | C[C@H]1CC(=O)O[C@@H](C)[C@H](O)\C=C\C(=O)O[C@@H](C)[C@H](O)\C=C\C(=O)O1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic [1, 2].
- Cell-cell adhesion inhibitor [1, 2].
- Antimetastatic compound [1, 2, 5].
- Antifungal [3].
- Antimicrobial [4].
Product References
- Macrosphelide, a novel inhibitor of cell-cell adhesion molecule. I. Taxonomy, fermentation, isolation and biological activities: M. Hayashi, et al.; J. Antibiot. 48, 1435 (1995)
- Macrosphelide, a novel inhibitor of cell-cell adhesion molecule. II. Physiochemical properties and structural elucidation: S. Takamatsu, et al.; J. Antibiot. 49, 95 (1996)
- Production of macrosphelide A by the mycoparasite Coniothyrium minitans: MP. McQuilken, et al.; FEMS Microbiol. Lett. 14, 219 (2003)
- Antimicrobial activity of Coniothyrium minitans and its macrolide antibiotic macrosphelide A: N. Tomprefa, et al.; J. Appl. Microbiol. 106, 2048 (2009)
- Enantioselective total synthesis of macrosphelides A and E: K.R. Prasad & P. Gutala; Tetrahedron 67, 4514 (2011)
- Development of an advanced synthetic route to macrosphelides and its application to the discovery of a more potent macrosphelide derivative: Y.M. Heo, et al.; Molecules 19, 15572 (2014)
- Design and synthesis of a macrosphelide A-biotin chimera: H. Yun, et al.; Org. Biomol. Chem. 12, 7127 (2014)
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