Rifamycin AF-DA

CHF 150.00
In stock
AG-CN2-0328-M01010 mgCHF 150.00
AG-CN2-0328-M05050 mgCHF 600.00
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Product Details
Synonyms Rifamycin AF/DA; 3-Formyl-25-desacetylrifamycin; 25-O-Deacetyl-3-formylrifamycin SV; NSC 145635
Product Type Chemical
Properties
Formula

C36H45NO12

MW 683.7
CAS 16783-97-4
Source/Host Chemicals Semisynthetic.
Purity Chemicals ≥90% (HPLC)
Appearance Red powder.
Solubility Soluble in DMSO, aqueous acetonitrile or ethanol.
Identity Determined by 1H-NMR and MS.
InChi Key GGZYOFVKHSKDIP-KUJRJRTCSA-N
Smiles OC1=C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)O)O)=O)C(C([H])=O)=C(O)C3=C4C(O[C@@]2(C)C4=O)=C(C)C(O)=C31
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light.
Protect from light when in solution.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Ansamycin antibiotic.
  • Intermediate of rifampicin.
  • Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).
  • Effective against mycobacteria. Therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.
Product References
  1. Rifamycins: A General View: S. Riva & L.G. Silvestri; Ann. Rev. Microbiol. 26, 199 (1972)
  2. Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
  3. Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)
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