AdipoGen Life Sciences

Rifamycin AF-DA

CHF 150.00

In stock

AG-CN2-0328-M01010 mgCHF 150.00

AG-CN2-0328-M05050 mgCHF 600.00

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Product Details
Synonyms	Rifamycin AF/DA; 3-Formyl-25-desacetylrifamycin; 25-O-Deacetyl-3-formylrifamycin SV; NSC 145635
Product Type	Chemical
Properties
Formula	C₃₆H₄₅NO₁₂
MW	683.7
CAS	16783-97-4
Source/Host Chemicals	Semisynthetic.
Purity Chemicals	≥90% (HPLC)
Appearance	Red powder.
Solubility	Soluble in DMSO, aqueous acetonitrile or ethanol.
Identity	Determined by ¹H-NMR and MS.
InChi Key	GGZYOFVKHSKDIP-KUJRJRTCSA-N
Smiles	OC1=C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)O)O)=O)C(C([H])=O)=C(O)C3=C4C(O[C@@]2(C)C4=O)=C(C)C(O)=C31
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry. Protect from light. Protect from light when in solution.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Ansamycin antibiotic.
Intermediate of rifampicin.
Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).
Effective against mycobacteria. Therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.

Product References

Rifamycins: A General View: S. Riva & L.G. Silvestri; Ann. Rev. Microbiol. 26, 199 (1972)
Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)

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