AdipoGen Life Sciences

Rifamycin AG

CHF 150.00

In stock

AG-CN2-0329-M01010 mgCHF 150.00

AG-CN2-0329-M05050 mgCHF 600.00

More Information
Product Details
Synonyms	NCI 144-111; 4-[(Aminoiminomethyl)azo]-4-deoxy-rifamycin
Product Type	Chemical
Properties
Formula	C₃₈H₄₉N₅O₁₁
MW	751.8
CAS	38128-51-7
Source/Host Chemicals	Semisynthetic.
Purity Chemicals	≥98% (HPLC)
Appearance	Red powder.
Solubility	Soluble in DMSO, aqueous acetonitrile or ethanol.
Identity	Determined by ¹H-NMR and MS.
InChi Key	LGCZXXFOLXAQNH-AYTZBZETSA-N
Smiles	O=C1C(N2)=C/C(C3=C1C(O)=C(C)C(O[C@]4(C)O/C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)\C2=O)=C3C4=O)=N\NC(N)=N
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry. Protect from light. Protect from light when in solution.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Ansamycin antibiotic.
Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).
Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.

Product References

Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)
Interaction of rifamycins with mammalian nucleic acid polymerizing enzymes: V.S. Sethi & P. Okano; Biochim. Biophys. Acta. 454, 230 (1976)

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