Rifamycin AG

CHF 150.00
In stock
AG-CN2-0329-M01010 mgCHF 150.00
AG-CN2-0329-M05050 mgCHF 600.00
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Product Details
Synonyms NCI 144-111; 4-​[(Aminoiminomethyl)​azo]​-​4-​deoxy-rifamycin
Product Type Chemical
Properties
Formula

C38H49N5O11

MW 751.8
CAS 38128-51-7
Source/Host Chemicals Semisynthetic.
Purity Chemicals ≥98% (HPLC)
Appearance Red powder.
Solubility Soluble in DMSO, aqueous acetonitrile or ethanol.
Identity Determined by 1H-NMR and MS.
InChi Key LGCZXXFOLXAQNH-AYTZBZETSA-N
Smiles O=C1C(N2)=C/C(C3=C1C(O)=C(C)C(O[C@]4(C)O/C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)\C2=O)=C3C4=O)=N\NC(N)=N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light.
Protect from light when in solution.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Ansamycin antibiotic.
  • Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).
  • Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.
Product References
  1. Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
  2. Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)
  3. Interaction of rifamycins with mammalian nucleic acid polymerizing enzymes: V.S. Sethi & P. Okano; Biochim. Biophys. Acta. 454, 230 (1976)
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