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AdipoGen Life Sciences
W-5 . hydrochloride
70
CHF
CHF 70.00
In stock
AG-CR1-0003-M0055 mgCHF 70.00
AG-CR1-0003-M02525 mgCHF 210.00
| Product Details | |
|---|---|
| Synonyms | N-(6-Aminohexyl)-1-naphthalenesulfonamide . HCl |
| Product Type | Chemical |
| Properties | |
| Formula |
C16H22N2O2S . HCl |
| MW | 306.4 . 36.5 |
| CAS | 61714-25-8 |
| Purity Chemicals | ≥98% (NMR) |
| Appearance | White to off-white crystalline solid. |
| Solubility | Soluble in DMSO or 100% ethanol (slightly soluble). |
| InChi Key | HOCSVIGHWPLMFC-UHFFFAOYSA-N |
| Smiles | [Cl-].[NH3+]CCCCCCNS(=O)(=O)C1=C2C=CC=CC2=CC=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Hygroscopic. Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Calmodulin antagonist [1-3].
- Cell proliferation inhibitor [1].
- Ca2+/calmodulin-regulated phosphodiesterase (PDE I) inhibitor [3].
- Myosin light chain kinase (MLCK) inhibitor [4].
Product References
- N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation: H. Hidaka, et al.; PNAS 78, 4354 (1981)
- W-5 and quin 2-AM reverse the inhibitory effect of insulin on lipolysis due to dibutyryl cAMP: H. Goko & A. Matsuoka; Diabetes Res. Clin. Pract. 44, 101 (1999)
- Calmodulin antagonism and growth-inhibiting activity of triphenylethylene antiestrogens in MCF-7 human breast cancer cells: A. Gulino, et al.; Cancer Res. 46, 6274 (1986)
- Hydrophobic regions function in calmodulin-enzyme(s) interactions.: T. Tanaka & H. Hidaka ; J. Biol. Chem. 255, 11078 (1980)
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