Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
AdipoGen Life Sciences
Compound 112254
120
CHF
CHF 120.00
In stock
AG-CR1-0155-M01010 mgCHF 120.00
AG-CR1-0155-M05050 mgCHF 480.00
| Product Details | |
|---|---|
| Synonyms | 4-(tert-Butyl)-N-(3-(4-(4-methoxybenzyl)piperazin-1-yl)-3-oxopropyl)benzamide |
| Product Type | Chemical |
| Properties | |
| Formula |
C26H35N3O3 |
| MW | 437.6 |
| CAS | 949745-75-9 |
| Purity Chemicals | ≥98% (NMR) |
| Appearance | White crystalline solid. |
| Solubility | Soluble in DMSO, 100% ethanol, methanol or dichloromethane. Insoluble in water. |
| Identity | Determined by 1H-NMR. |
| InChi Key | XBEMZEZVTNPLQI-UHFFFAOYSA-N |
| Smiles | COC1=CC=C(CN2CCN(CC2)C(=O)CCNC(=O)C2=CC=C(C=C2)C(C)(C)C)C=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Prod. No. AG-CR1-0154) [1, 2].
- Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells [1].
- Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms [1].
Product References
- A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity: M. Okada-Iwabu, et al.; Nature 503, 493 (2013)
- Cell Biology. Ronning after the adiponectin receptors: W.L. Holland & P.E. Scherer; Science 342, 1460 (2013)
Related Products
