anti-CD8-α (mouse), mAb (53-6)

CHF 192.00
In stock
ANC-260-020100 µgCHF 192.00
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Product Details
Product Type Monoclonal Antibody
Clone 53-6
Isotype Rat IgG2aκ
Immunogen/Antigen murine thymocytes/splenocytes.

Flow Cytometry

Crossreactivity Mouse
Formulation 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Isotype Negative Control

Rat IgG2a Isotype Control

Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
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Product Specification Sheet
Datasheet Download PDF

CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-α chains binds to Class I MHC molecules α-3 domains. Defects in CD8A are a cause of familial CD8 deficiency [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.

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