Ancell

anti-CD8-α (mouse), mAb (53-6) (FITC)

CHF 306.00
In stock
ANC-260-040120 testsCHF 306.00
More Information
Product Details
Product Type Monoclonal Antibody
Properties
Clone 53-6
Isotype Rat IgG2aκ
Immunogen/Antigen murine thymocytes/splenocytes.
Label/Conjugates FITC
Application Flow Cytometry
ELISA
Crossreactivity Mouse
Formulation 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-α chains binds to Class I MHC molecules α-3 domains. Defects in CD8A are a cause of familial CD8 deficiency [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.

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