Ancell

anti-CD8-α (mouse), mAb (53-6) (Biotin)

CHF 306.00

In stock

ANC-260-030100 µgCHF 306.00

More Information
Product Details
Product Type	Monoclonal Antibody
Properties
Clone	53-6
Isotype	Rat IgG2aκ
Immunogen/Antigen	murine thymocytes/splenocytes.
Label/Conjugates	Biotin
Application	Flow Cytometry ELISA
Crossreactivity	Mouse
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-α chains binds to Class I MHC molecules α-3 domains. Defects in CD8A are a cause of familial CD8 deficiency [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.

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