anti-LTβR (human), mAb (ANCLTR2/9E2) (preservative free)

CHF 236.00
In stock
ANC-267-820100 µgCHF 236.00
More Information
Product Details
Synonyms Lymphotoxin-β Receptor; Tumor Necrosis Factor Receptor 2 Related Protein; Tumor Necrosis Factor C Receptor; Tumor Necrosis Factor Receptor Superfamily Member 3; TNFRSF3
Product Type Monoclonal Antibody
Properties
Clone ANCLTR2/9E2
Isotype Mouse IgG1κ
Immunogen/Antigen Recombinant Human LT.
Label/Conjugates Preservative Free
Application

Flow Cytometry
ELISA

Crossreactivity Human
Formulation 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl
Isotype Negative Control

Mouse IgG1 Isotype Control (preservative free)

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

The LTβR activates two different NF-κB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTβR activates the classical NF-κB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1β. However, LTβR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.

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