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Ancell
anti-CD3 (mouse), mAb (145-2C11) (preservative free)
260
CHF
CHF 260.00
In stock
ANC-703-820100 µgCHF 260.00
| Product Details | |
|---|---|
| Synonyms | CD3ε; CD3e |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 145-2C11 |
| Isotype | Hamster IgG |
| Immunogen/Antigen | Mouse BM10-37 T cell membrane prep. |
| Label/Conjugates | Preservative Free |
| Application |
Flow Cytometry |
| Crossreactivity | Mouse |
| Specificity |
Clone 145-2C11 binds to an extracellular epitope of the 25 kd CD3ε molecule present on murine T cells. |
| Purity | ≥95% (SDS-PAGE) |
| Purity Detail | Protein G purified. |
| Formulation | 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Ancell Corporation. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
CD3 molecules associate with T cell receptors and provide intracellular signaling mechanism. Cross linking cell surface CD3 with soluble or immobilized antibody clone 145-2C11 can activate this mechanism.
Product References
- Identification of a monoclonal antibody specific for a murine T3 polypeptide: O. Leo, et al.; PNAS 84, 1374 (1987)
- T cell antigen receptor phosphorylation induced by an anti-receptor antibody: L.E. Samelson, et al.; J. Immunol. 139, 2708 (1987)
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