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BellBrook
Enzolution™ DDX3 ATPase FI Assay System
CHF 0.00
In stock
BBL-3038-FI-1K1000 assaysCHF 2'108.00
BBL-3038-FI-10K10000 assaysCHF 7'739.00
BBL-3038-FI-100K10 x 10000 assaysINQ
Figure 1: Schematic Overview of the DDX3 ATPase Assay System with the Transcreener® ADP2 Assays.
| Product Details | |
|---|---|
| Synonyms | ATP-dependent RNA Helicase DDX3X; DEAD Box Protein 3, X-chromosomal; DDX3X |
| Product Type | Kit |
| Properties | |
| Application Set | Compound Screening |
| Crossreactivity | Human |
| Quantity |
1000 assays/384wells (BBL-3038-FI-1K) 10000 assays/384wells (BBL-3038-FI-10K) 100000 assays/384wells (BBL-3038-FI-100K) Note: The exact number of assays depends on enzyme reaction conditions. |
| Detection Type | Fluorescence intensity |
| Kit Contains |
- DDX3 (human) (rec.) Enzyme |
| Other Product Data |
Click here for Complete Information from the Original Manufacturer |
| Declaration | Manufactured by BellBrook Labs. |
| Accession Number | O00571 |
| Shipping and Handling | |
| Shipping | DRY ICE |
| Short Term Storage | -20°C |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Documents | |
| Manual |
 Download PDF |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
The Enzolution DDX3 ATPase Assay System provides researchers with an assay tool that will simplify and advance their exploration of novel DDX3/innate immunity modulators. DDX3, a DEAD Box helicase protein characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), is an ATP-dependent RNA helicase that unwinds RNA-RNA and RNA-DNA duplexes. The assay system includes DDX3 enzyme, RNA substrate, assay plates, and buffers to generate a DDX3 enzymatic reaction to produce ADP. The Transcreener ADP FI Assay (sold separately) is a far-red, competitive assay that directly measures ADP production to determine enzymatic activity with a fluorescence intensity (FI) readout. The Transcreener ADP FI Assay is not included in the Enzolution Assay System but is available for separate purchases. The Transcreener ADP assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.
When purchasing the DDX3 ATPase FI Assay System, it is important to choose the assay system readout corresponding to the FI configuration of your Transcreener ADP2 Assay Kit!
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