BioViotica

(+)-Flavipucine

CHF 130.00
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BVT-0279-M0011 mgCHF 130.00
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Product Details
Synonyms Glutamicine; Glutamycin; FRT-B; 6-Methyl-2-(3-methyl-1-oxobutyl)-1-oxa-5-azaspiro[2.5]oct-6-ene-4,8-dione
Product Type Chemical
Properties
Formula

C12H15NO4

MW 237.3
CAS 72597-14-9
Source/Host Chemicals Isolated from Phoma sp. BS 7204.
Purity Chemicals ≥96% (HPLC, 1H-NMR)
Appearance White to off-white solid.
Solubility Soluble in DMSO, methanol or dichloromethane.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key DWCXXICTUDDKTB-ZYHUDNBSSA-N
Smiles CC(C)CC(=O)[C@H]1O[C@@]11C(=O)NC(C)=CC1=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Phytotoxin (Fruit rot toxin).
  • Antibiotic.
  • Antibacterial and antifungal compound.
Product References
  1. Synthesis and biological activity of flavipucine analogs: N.N. Girotra, et al.; J. Med. Chem. 23, 209 (1980)
  2. Isolation and identification of fruit rot toxins from the fungus-caused Macrophoma fruit rot of apple: T. Sassa, et al.; Agric. Biol. Chem. 47, 1155 (1983)
  3. The biosynthesis of plant alkaloids and nitrogenous microbial metabolites: R.B. Herbert; Nat. Prod. Rep. 7, 105 (1990)
  4. Flavipucine and brunnnescin, two antibiotics from cultures of the mycophilic fungus Cladobotryum rubrobrunnescens: C. Wagner, et al.; J. Biosci. 50, 358 (1995)
  5. Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreus: M. Gressler, et al.; Chem. Biol. 18, 198 (2011)
  6. (+)-Flavipucine, the missing member of the pyridione epoxide family of fungal antibiotics: S. Loesgen, et al.; Eur. J. Chem. 26, 5156 (2011)
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