BioViotica

MM 47755

CHF 145.00
In stock
BVT-0282-M0011 mgCHF 145.00
BVT-0282-M0055 mgCHF 575.00
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Product Details
Synonyms 6-Desoxy-8-O-methylrabelomycin; (R)-3-Hydroxy-8-methoxy-3-methyl-3,4-dihydro-tetraphene-1,7,12(2H)-trione
Product Type Chemical
Properties
Formula

C20H16O5

MW 336.3
CAS 117620-87-8
Source/Host Chemicals Isolated from Streptomyces sp. Gö 40/14.
Purity Chemicals ≥98% (HPLC)
Appearance Yellow solid.
Solubility Soluble in DMSO, methanol or acetone.
Identity Determined by 1H-NMR and optical rotation.
Declaration Manufactured by BioViotica.
InChi Key XZLGWJORNHETKI-HXUWFJFHSA-N
Smiles COC1=CC=CC2=C1C(=O)C1=C(C2=O)C2=C(C[C@@](C)(O)CC2=O)C=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Antibiotic.
  • Angucyclinone.
  • Antibacterial and antifungal.
Product References
  1. 6-Deoxy-8-O-methylrabelomycin and 8-O-methylrabelomycin from a Streptomyces species: Y. Shigihara, et al.; J. Antibiot. 41, 1260 (1988)
  2. MM 47755, a new benz[a]anthracene antibiotic from a streptomycete: M.L. Gilpin, et al.; J. Antibiot. 42, 627 (1989)
  3. Remote stereochemical control in asymmetric Diels - Alder reactions: Synthesis of the angucycline antibiotics, (-)-tetrangomycin and MM 47755: J.S. Landells, et al.; THL 44, 5193 (2003)
  4. Total synthesis of (-)-8-O-methyltetrangomycin (MM 47755): C. Kesenheimer & U. Groth; Org. Lett. 8, 2507 (2006)
  5. Angucyclinone antibiotics: total syntheses of YM-181741, (+)-ochromycinone, (+)-rubiginone B2, (-)-tetrangomycin, and MM-47755: K.P. Kaliappan & V. Ravikumar; J. Org. Chem. 72, 6116 (2007)
  6. Search method for inhibitors of Staphyloxanthin production by methicillin-resistant Staphylococcus aureus: K. Sakai, et al.; Biol. Pharm. Bull. 35, 48 (2012)
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