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BioViotica
Antibiotic PF 1052
130
CHF
CHF 130.00
In stock
BVT-0338-C500500 µgCHF 130.00
BVT-0338-M0011 mgCHF 230.00
| Product Details | |
|---|---|
| Synonyms | (E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methylene)-1-methylpyrrolidine-2,4-dione |
| Product Type | Chemical |
| Properties | |
| Formula |
C26H39NO4 |
| MW | 429.6 |
| CAS | 147317-15-5 |
| Source/Host Chemicals | Isolated from Phoma sp. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Light brown solid. |
| Solubility | Soluble in DMSO, methanol, methylene chloride, or chloroform (all at 10mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | NPWKEUKXVOMELT-XTQSDGFTSA-N |
| Smiles | CCC(C)C1N(C)C(=O)\C(=C(\O)C2C(C=CC3CC(C)CC(C)C23)C2(C)OC2C)C1=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light when in solution. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic.
- Antibacterial, antifungal and phytotoxic.
- Anti-inflammatory agent. Described as neutrophil migration inhibitor.
Product References
- New antibiotic substance PF1052 and its production: T. Sasaki, et al.; Patent JP04316578A (1992)
- Spylidone, a novel inhibitor of lipid droplet accumulation in mouse macrophages produced by Phoma sp. FKI-1840.: N. Koyama et al.; J. Antibiot. 58, 338 (2005)
- Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library: X. Wang, et al.; Dis. Model Mech. 7, 163 (2014)
- Loss of cftr function leads to pancreatic destruction in larval zebrafish: A. Navis, et al.; Dev. Biol. 399, 237 (2015)
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