Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
BioViotica
Saquayamycin B1
115
CHF
CHF 115.00
In stock
BVT-0382-C500500 µgCHF 115.00
BVT-0382-M0011 mgCHF 180.00
BVT-0382-M0055 mgCHF 540.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C31H32O12 |
| MW | 596.6 |
| CAS | 99260-68-1 |
| Source/Host Chemicals | Isolated from Streptomyces nodosus. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Orange powder. |
| Solubility | Soluble in DMSO, methanol or chloroform. |
| Identity | Determined by 1H-NMR and UV. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | CTSPXNCFVRSKKD-IGVHUSDSSA-N |
| Smiles | CC1OC(CC2OC3CC(=O)C(C)OC3OC12)C1=CC=C2C(=O)C3=C(C=C[C@]4(O)C[C@@](C)(O)CC(=O)[C@]34O)C(=O)C2=C1O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Angucycline antibiotic.
- Antibacterial.
- Antitumor compound.
- Active against Gram-positive bacteria and P388 leukaemia cells.
- Farnesyl-protein transferase inhibitor.
- Inhibitor of nitric oxide synthase (NOS) (shown for Saquayamycin A1).
Product References
- Saquayamycins, new aquayamycin-group antibiotics: T. Uchida, et al.; J. Antibiot. 38, 1171 (1985)
- Angucycline group antibiotics: J. Rohr & R. Thiericke; Nat. Prod. Rep. 9, 103 (1992) (Review)
- Isolation of novel saquayamycins as inhibitors of farnesyl-protein transferase: R. Sekizawa, et al.; J. Antibiot. 49, 487(1996)
- Identification of inhibitors of inducible nitric oxide synthase from microbial extracts: A. A. Khisal, et al.; J. Antibiot. 53, 496 (2000)
- Moromycins A and B: M. S. Abdelfattah, et al.; J. Nat. Prod. 71, 1569 (2008)
Related Products
