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Chemodex
3-(2-Benzothiazolyl)-7-(diethylamino) coumarin
Product Details | |
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Synonyms | Coumarin 6; Coumarin VI; Coumarin 540; 3-(2-Benzothiazolyl)-N,N-diethylumbelliferylamine |
Product Type | Chemical |
Properties | |
Formula |
C20H18N2O2S |
MW | 350.43 |
CAS | 38215-36-0 |
Source/Host Chemicals | Synthetic. |
Purity Chemicals | ≥98% (HPLC) |
Appearance | Copper or orange powder or crystalline powder. |
Solubility | Soluble in DMSO, DMF or alcohols. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | VBVAVBCYMYWNOU-UHFFFAOYSA-N |
Smiles | CCN(CC)C1=CC=C2C=C(C3=NC4=C(S3)C=CC=C4)C(=O)OC2=C1 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
3-(2-Benzothiazolyl)-7-(diethylamino) coumarin (Coumarin 6) is a derivative of coumarin with a benzothiazolyl group at the position 3. It emits fluorescence in solid and solution state and is used as fluorescent dye to stain organelles. Coumarin 6 is majorly used as blue-green spectrum laser dye and is microenvironment sensitive. Coumarin 6 can be used in the labeling and visualization of polymeric nanoparticles in biological applications, such as oral drug delivery systems for cancer. It can also be used in development of electroluminescent devices such as organic light emitting diodes (OLEDs). Spectral data: λem 505nm in ethanol (Lasing peak 534nm, lasing range 515-558nm (DMSO), pump source XeCl (308nm)).
(1) J. Eley, et al.; J. McLane; Drug Delivery 11, 255 (2004) | (2) J. Panyam, et al.; Int. J. Pharm., 262, 1 (2003) | (3) C. Lombry, et al.; J. Contr. Release, 83, 331 (2002) | (4) D. Li, et al.; Mat. Lett. 59, 2120 (2005) | (5) S. Fery-Forgues, et al.; J. Fluoresc. 18, 619 (2008) | (6) B.S. Lee, et al.; J. Drug Deliv. 2011 (2011) | (7) K.L. Chen, et al.; Sci. Rep. 8, 16740 (2018)