Colcemid

CHF 281.00
In stock
CDX-C0022-M02525 mgCHF 281.00
More Information
Product Details
Synonyms Demecolcine; N-Deacetyl-N-methylcolchicine
Product Type Chemical
Properties
Formula C21H25NO5
MW 371.43
CAS 477-30-5
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (HPLC)
Appearance Light yellow powder.
Solubility Soluble in chloroform.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key NNJPGOLRFBJNIW-UHFFFAOYSA-N
Smiles CNC1CCC2=CC(OC)=C(OC)C(OC)=C2C2=CC=C(OC)C(=O)C=C12
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

Depolymerizes microtubules and blocks mitosis at metaphase. Often in karyotyping and cell cycle research it is desirable to increase the yield of mitotic cells in a particular phase of the cell cycle. This can be achieved in a variety of ways with the most popular being the use of a cell cycle synchronizing agent such as demecolcine. Demecolcine will arrest cells in metaphase with no remarkable effect on the biochemical events in mitotic cells or in synchronized G1 and S phase cells. White blood cells are often treated with demecolcine to arrest cells in metaphase.

Product References

(1) K. Ray et al.; Eur. J. Biochem. 142, 577 (1984)

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