Cholesterol

CHF 77.00
In stock
CDX-C0249-G02525 gCHF 77.00
CDX-C0249-G100100 gCHF 306.00
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Product Details
Synonyms 3β-Hydroxy-5-cholestene; 5-Cholesten-3β-ol; Provitamin D; NSC 8798; Cholesterin
Product Type Chemical
Properties
Formula

C27H46O

MW 386.65
CAS 57-88-5
Source/Host Chemicals Synthetic.
Purity Chemicals ≥99%
Appearance White to off-white powder.
Solubility Soluble in chloroform, ether or pyridine. Insoluble in water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key HVYWMOMLDIMFJA-DPAQBDIFSA-N
Smiles CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Major component of all biological membranes. Essential structural component of mammalian cell membranes and required to establish proper membrane permeability and fluidity. In addition to its importance within cells, also serves as a precursor for the biosynthesis of steroid hormones, bile acids, and vitamin D. Regulates the function of the transporters and signaling proteins present on the plasma membrane. Implicated in cell signaling processes, assisting in the formation of lipid rafts in the plasma membrane, which brings receptor proteins in close proximity with high concentrations of second messenger molecules. Used to prepare immune-stimulating complexes to enhance cellular and humoral responses and suitable for use in liposome preparations. Binds to and affects the gating of a number of ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel. Also activates the estrogen-related receptor alpha, and may be the endogenous ligand for the receptor. Has been shown to be an important factor in cancer, obesity, neurodeneration and inflammatory diseases.

Product References

(1) I. Levitan, et al.; Front. Physiol. 5, 65 (2014) | (2) J. Zhang & Q. Liu; Protein Cell 6, 254 (2015) | (3) A.R. Tall L. Yvan-Charvet; Nat. Rev. Immunol. 15, 104 (2015) | (4) W. Wei, et al.; Cell Metab. 23, 479 (2016) | (5) V. Ribas, et al.; Clin. Transl. Med. 5, 22 (2016) | (6) L. Raccosta, et al.; Cancer Immunol. Immunother. 65, 111 (2016)

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