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Chemodex
Cholesteryl acetate
155
CHF
CHF 155.00
In stock
CDX-C0359-G05050 gCHF 155.00
CDX-C0359-G100100 gCHF 245.00
| Product Details | |
|---|---|
| Synonyms | Cholesterol acetate; 3β-Acetoxy-5-cholestene; 3β-Hydroxy-5-cholestene 3-acetate; 5-Cholesten-3β-ol 3-acetate; NSC 8799 |
| Product Type | Chemical |
| Properties | |
| Formula | C29H48O2 |
| MW | 428.69 |
| CAS | 604-35-3 |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White solid. |
| Solubility | Soluble in chloroform. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | XUGISPSHIFXEHZ-JWAONGLTSA-N |
| Smiles | C[C@H](CCCC(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(C)=O)CC[C@]4(C)[C@@]3([H])CCC21C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice |
Keep cool and dry. Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Cholesteryl acetate is a normal human cholesteryl ester present in diverse fluids and organs. Cholesteryl acetate is also present in foods. Food oxidation affects the quality and safety of the human diet by generating compounds with biological activities that can adversely affect health. In particular the susceptibility of cholesterol to oxidation is well known, certain products of cholesterol oxidation have been reported to produce cytotoxic, angiotoxic and carcinogenic effects. Cholesteryl ester (CE) is the major transport and storage form of cholesterol in lipoprotein particles and most cell types. Molecular composition of CE species is of high interest for arteriosclerosis research, i. e. , as components of lipoprotein subclasses or in studies investigating the mechanisms involved in the generation of lipid laden foam cells. Thus, it has been shown that CE species in circulating plasma are strongly correlated with development of coronary heart disease. Cholesteryl acetate is used in cosmetics or pharmaceuticals.
Product References
(1) P. Sawzik & B.M. Craven; Acta Cryst. 35, 895 (1979) | (2) E.G. Perkins, et al.; Lipids 16, 609 (1981) | (3) P.J. Dolphin, et al.; Atheroscler. 51, 109 (1984) | (4) B. Sjostrom, et al.; J. Pharm. Sci. 82, 584 (1993) | (5) B. Sjostrom, et al.; Int. J. Pharm. 94, 89 (1993) | (6) B. Sjostrom, et al.; Pharm. Res. 12, 39 (1995) | (7) F.P. Ballistreri, et al.; Steroids 71, 565 (2006) | (8) D.A. Aleksandrov, et al.; FEBS J. 273, 548 (2006) | (9) I. Gvozdovskyy & L. Lisetski; Europ. Phys. J. E 24, 211 (2007)
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