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Chemodex
CPM
264
CHF
CHF 264.00
In stock
CDX-D0042-M05050 mgCHF 264.00
CDX-D0042-M250250 mgCHF 1'194.00
| Product Details | |
|---|---|
| Synonyms | 7-Diethylamino-3-(4-maleimidylphenyl)-4-methylcoumarin |
| Product Type | Chemical |
| Properties | |
| Formula | C24H22N2O4 |
| MW | 402.44 |
| CAS | 76877-33-3 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | Yellow solid. |
| Solubility | Soluble in DMSO, DMF, acetonitrile or chloroform. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | YGIABALXNBVHBX-UHFFFAOYSA-N |
| Smiles | CCN(CC)C1=CC2=C(C=C1)C(C)=C(C(=O)O2)C1=CC=C(C=C1)N1C(=O)C=CC1=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Widely used blue fluorescent thiol-reactive dye (Ex/Em: 384/470nm). This maleimide derivative of coumarin is essentially non-fluorescent until it reacts with thiols, making it possible to quantify thiols without a separation step. Good energy acceptor from tryptophan and a good energy donor to fluorescein. Used to monitor release of thiols and to distinguish proliferating cancer cells by nucleolar protein staining.
Product References
(1) C.C. Chung; Assay and Drug Devel. Techn. 6(3), 361 (2008) | (2) O. Khersonsky et al.; ChemBioChem 7(1), 49 (2006) | (3) J.E.T. Corrie et al.; J. Chem. Soc. Trans., Perkin Trans. 1, 2975 (1994)
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