CPM

CHF 249.00
In stock
CDX-D0042-M05050 mgCHF 249.00
CDX-D0042-M250250 mgCHF 1'123.00
More Information
Product Details
Synonyms 7-Diethylamino-3-(4-maleimidylphenyl)-4-methylcoumarin
Product Type Chemical
Properties
Formula C24H22N2O4
MW 402.44
CAS 76877-33-3
Source/Host Chemicals Synthetic.
Purity Chemicals ≥95% (HPLC)
Appearance Yellow solid.
Solubility Soluble in DMSO, DMF, acetonitrile or chloroform.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key YGIABALXNBVHBX-UHFFFAOYSA-N
Smiles CCN(CC)C1=CC2=C(C=C1)C(C)=C(C(=O)O2)C1=CC=C(C=C1)N1C(=O)C=CC1=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Widely used blue fluorescent thiol-reactive dye (Ex/Em: 384/470nm). This maleimide derivative of coumarin is essentially non-fluorescent until it reacts with thiols, making it possible to quantify thiols without a separation step. Good energy acceptor from tryptophan and a good energy donor to fluorescein. Used to monitor release of thiols and to distinguish proliferating cancer cells by nucleolar protein staining.

Product References

(1) C.C. Chung; Assay and Drug Devel. Techn. 6(3), 361 (2008) | (2) O. Khersonsky et al.; ChemBioChem 7(1), 49 (2006) | (3) J.E.T. Corrie et al.; J. Chem. Soc. Trans., Perkin Trans. 1, 2975 (1994)

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