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Chemodex
6,8-Difluoro-7-hydroxy-4-methylcoumarin
Product Details | |
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Synonyms | DiFMU; Marina blue; 6,8-Difluoro-7-hydroxy-4-methyl-2H-1-benzopyran-2-one |
Product Type | Chemical |
Properties | |
Formula | C10H6F2O3 |
MW | 212.15 |
CAS | 215868-23-8 |
Source/Host Chemicals | Synthetic. |
Purity Chemicals | ≥98% (HPLC) |
Appearance | White to off-white solid. |
Solubility | Soluble in DMSO, DMF or methanol. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | LLENVBUPWUQAGL-UHFFFAOYSA-N |
Smiles | FC1=C2C(C(C)=CC(O2)=O)=CC(F)=C1O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
Keep cool and dry. Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
UV-excitable blue fluorescent blue dye. Used to label Aβ-proteins, bacteria, histone deacetylase, nucleic acids, peptides, proteins and sugar chains. Applied in studies amplifying/detecting nucleic acid sequences, analyzing peptides, sugar chains, detecting bacteria, as a substrate for measuring acyl protein thioesterase (APT1), α-amylase, aryl sulfatases, β-galactosidases, guanidinobenzoatase, β-lactamase, lipase, phosphatases, protein kinases and xylanase activity. Used in diagnosing/treating traumatic brain injury, treating amyloidogenic disease and as temperature sensor. Can be used as a reference standard for substrates derived from this blue-fluorescent dye (CDX-D0164). Spectral data: &lambda|ex=362, &lambda|em=464.
(1) W.-C. Sun, et al.; Bioorg. Med. Chem. Lett. 8, 3107 (1998) | (2) A. Pashkova, et al.; Anal. Chem. 76, 4550 (2004) | (3) V. Ahmed, et al.; Anal. Biochem. 340, 80 (2005) | (4) S.-H. Kang, et al.; Anal. Biochem. 360, 1 (2007) | (5) J. Szucs, et al.; Analyst 134, 1601 (2009) | (6) R.W. Sabnis; Handbook of Fluorescent Dyes and Probes (2015)