Dihydrofluorescein diacetate

CHF 110.00
In stock
CDX-D0122-G0011 gCHF 110.00
CDX-D0122-G01010 gCHF 414.00
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Product Details
Product Type Chemical
Formula C24H18O7
MW 418.4
CAS 35340-49-9
Source/Host Chemicals Synthetic.
Purity Chemicals ≥97% (NMR)
Appearance Solid.
Solubility Soluble in chloroform.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Smiles CC(=O)OC1=CC2=C(C=C1)C(C1=C(O2)C=C(OC(C)=O)C=C1)C1=C(C=CC=C1)C(O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Dihydrofluorescein diacetate is a fluorescent probe for detecting intracellular oxidants. It is hydrolyzed by cellular esterases to dihydrofluorescein and is then oxidized to fluorescein primarily by H2O2. Dihydrofluorescein diacetate might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. Cell-loading studies indicate that dihydrofluorescein achieves higher intracellular concentrations than the other redox sensors such as Dihydrorhodamine 123 (Ex/Em: 490/514nm).

Product References

(1) P.P. Williams & R.L. Stolzenberg; Applied Microbiology 23(4), 745-9 (1972) | (2) S.L. Hempel, et al.; Free Radical Biology & Medicine 27(1/2), 146-159 (1999) | (3) Y. O'Malley et al.; Free Radical Biology & Medicine 36(1), 90-100 (2004)

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