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Chemodex
trans-11-Methyl-2-dodecenoic acid
Product Details | |
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Synonyms | trans-DSF; trans-δ2-11-Methyl-dodecenoic; 11-Methyl-2-trans-Dodecenoic acid; 11-methyl-2E-dodecenoic acid |
Product Type | Chemical |
Properties | |
Formula |
C13H24O2 |
MW | 212.3 |
CAS | 677354-24-4 |
Source/Host Chemicals | Synthetic. |
Purity Chemicals | ≥98% |
Appearance | Off-white crystalline powder. |
Solubility | Soluble in ethanol (30mg/ml), DMSO or DMF. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | SNTXNGAQYNSTHI-PKNBQFBNSA-N |
Smiles | CC(C)CCCCCCC/C=C/C(O)=O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | -20°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
trans-Δ2-11-methyl-Dodecenoic acid is the conformational isomer of cis-Δ2-11-methyl-dodecenoic acid, a diffusible signal factor (DSF) in extracellular microbial and fungal communication systems. Both prokaryotes and eukaryotes depend on small signalling molecules for cell-cell communication. In a DSF bioassay, the minimum concentration of cis-Δ2-11-methyl-dodecenoic acid required for induction of a DSF biosensor was about 0.5 µM, which is 200-fold lower than that of trans-Δ2-11-methyl-dodecenoic acid and 20,000-fold lower than that of the corresponding saturated fatty acid (11-methyl-dodecanoic acid).
(1) L.H. Wang, et al.; Mol. Microbiol. 51, 903 (2004) | (2) K.B. Twomey, et al.; ISME J. 6, 939 (2012)