CHF 217.00
In stock
CDX-T0175-M02525 mgCHF 217.00
CDX-T0175-M100100 mgCHF 651.00
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Product Details
Synonyms BRN0072205; NSC147755; Coltramyl; 10-thio-Colchicoside; 2-Demethoxy-2-glucosidoxythiocolchicine
Product Type Chemical
Formula C27H33NO10S
MW 563.6
CAS 602-41-5
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (HPLC)
Appearance Light yellow to dark yellow powder.
Solubility Soluble in water (10 mg/ml).
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Smiles COC1=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C2CC[C@H](NC(C)=O)C3=CC(=O)C(SC)=CC=C3C2=C1OC
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +4°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Potent competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist. Described to be a muscle relaxant. Anti-inflammatory agent with analgesic properties. Shown to be an anticancer compound through inhibition of NF-κB and NF-κB-regulated gene products. Therapeutic option for the management of bone metastatic disease.

Product References

(1) J.M. Janbroers; Acta Ther. 13, 221 (1987) | (2) M. Carta, et al.; Neuropharmacology 51, 805 (2006) | (3) S. Reuter, et al.; Cancer Prev. Res. 3, 1462 (2010) | (4) O. Micheau, et al.; Br. J. Pharmacol. 165, 2124 (2012)

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