IL-17A (human):Fc (human) (rec.)

CHF 560.00
In stock
CHI-AG-40A-0066-C05050 µgCHF 560.00
 
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Product Details
Synonyms Interleukin-17A; Cytotoxic T-lymphocyte-associated Antigen 8; CTLA-8
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence The extracellular domain of human IL-17A (aa 24-155) is fused at the C-terminus to the Fc portion of human IgG1.
Crossreactivity Human
MW ~42kDa (SDS-PAGE)
Purity ≥90% (SDS-PAGE)
Endotoxin Content <0.06EU/μg purified protein (LAL test; Lonza).
Reconstitution Reconstitute with sterile water to a concentration of 1mg/ml.
Add 1x PBS to the desired protein concentration.
Formulation Lyophilized from 0.2μm-filtered solution in 1X PBS.
Other Product Data NCBI link AAH67505.1: Interleukin-17A (human)
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Interleukin-17A (IL-17A) exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblasts, the enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-κB and costimulation of T cell proliferation. Induces stromal cells to produce proinflammatory and hematopoietic cytokines.
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