anti-Acrolein [ACR], mAb (5F6)

CHF 518.00
In stock
JAI-MAR-020N20 µgCHF 518.00
 
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Product Details
Product Type Monoclonal Antibody
Properties
Clone 5F6
Isotype Mouse IgG1κ
Immunogen/Antigen ACR-modified keyhole-lympet hemocyanine.
Application Immunohistochemistry: Recommended concentration is 0.5-1μg/mL on paraffin sections.
Crossreactivity All
Human
Specificity Recognizes ACR-modified proteins (especially FDP-lysine type derivatives).
Purity Detail Protein A purified.
Formulation Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA.
Other Product Data Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Declaration Manufactured by JaICA.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 3 years after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Acrolein (ACR) is a representative carcinogenic aldehyde found ubiquitously in the environment and formed endogenously through oxidation reactions, such as lipid peroxidation and myeloperoxidasecatalyzed amino acid oxidation. ACR is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with ACR and lysine residue leads to the formation of numerous numbers of adducts, such as formyl-dehydropiperidino-lysine (FDP-lysine) type derivative.
Product References
  1. Protein-bound acrolein: Potential markers for oxidativestress: K. Uchida, et al.; PNAS 95, 4882 (1998)
  2. Protein-bound acrolein: A novel markers of oxidativestress in Alzheimer's Disease: Y. Noel, et al.; J. Neurochem. 72, 751 (1999)
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