anti-Malondialdehyde [MDA], mAb (1F83)

CHF 830.00
In stock
JAI-MMD-030N30 µgCHF 830.00
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Product Details
Product Type Monoclonal Antibody
Clone 1F83
Isotype Mouse IgG2aλ
Immunogen/Antigen MDA-modified keyhole-lympet hemocyanine.

Immunohistochemistry: Recommended concentration is 0.5-1μg/mL on paraffin sections.

Crossreactivity All

Recognizes MDA-modified proteins (especially DHP-lysine).

Purity Detail Protein A purified.
Formulation Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA.
Isotype Negative Control

Mouse IgG2a Isotype Control

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by JaICA.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 3 years after receipt when stored at -20°C.
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Malondialdehyde (MDA) is one of the major aldehyde derive from lipid peroxidation. MDA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with MDA and lysine residue leads to the formation of numerous numbers of adducts, such as dihydropyridine-lysine (DHP-lysine) type derivative.

Product References
  1. Immunochemical detection of a lipofuscin-like fluorophore derivered from malondialdehyde and lysine: S. Yamada, et al.; J. Lipid Res. 42, 1187 (2001)
  2. A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis: F. Yao, et al.; Nature Comm. 12, 7333 (2021)
  3. Synergy of intermittent fasting and ferroptosis inhibition dampens ‘cytokine storm’: H. Wang, et al.; Res. Square doi.org/10.21203/rs.3.rs-1697205/v1 ahead of print (2022)
  4. Membranes and deoxyribonucleic acid of hippocampal neurons damage due to low-density polyethylene microplastics in blood of Wistar rats: Y. Sincihu, et al.; Int. J. Health Sci. 6, 3490 (2022)
  5. Wistar Rats Hippocampal Neurons Response to Blood Low-Density Polyethylene Microplastics: A Pathway Analysis of SOD, CAT, MDA, 8-OHdG Expression in Hippocampal Neurons and Blood Serum Aβ42 Levels: Y. Sincihu, et al.; Neuropsych. Dis. Treat. 19, 73 (2023)
  6. Detection of Ferroptosis in Patient-Derived Tumor Models: W. Zhang & Y. Wang; Methods Mol. Biol. 2712, 187 (2023)
  7. Pyruvate kinase M2 nuclear translocation regulate ferroptosis-associated acute lung injury in cytokine storm: H. Wang, et al.; Res. Square doi.org/10.21203/rs.3.rs-3507704/v1 (2023)
  8. Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition: W. Cui, et al.; Nature Cell Biol. 26, 124 (2024)
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