anti-Malondialdehyde [MDA], mAb (1F83)
|Product Type||Monoclonal Antibody|
|Immunogen/Antigen||MDA-modified keyhole-lympet hemocyanine.|
Immunohistochemistry: Recommended concentration is 0.5-1μg/mL on paraffin sections.
Recognizes MDA-modified proteins (especially DHP-lysine).
|Purity Detail||Protein A purified.|
|Formulation||Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA.|
|Isotype Negative Control|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
|Declaration||Manufactured by JaICA.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Handling Advice||Avoid freeze/thaw cycles.|
|Use/Stability||Stable for at least 3 years after receipt when stored at -20°C.|
|Product Specification Sheet|
Malondialdehyde (MDA) is one of the major aldehyde derive from lipid peroxidation. MDA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with MDA and lysine residue leads to the formation of numerous numbers of adducts, such as dihydropyridine-lysine (DHP-lysine) type derivative.
- Immunochemical detection of a lipofuscin-like fluorophore derivered from malondialdehyde and lysine: S. Yamada, et al.; J. Lipid Res. 42, 1187 (2001)
- A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis: F. Yao, et al.; Nature Comm. 12, 7333 (2021)
- Synergy of intermittent fasting and ferroptosis inhibition dampens ‘cytokine storm’: H. Wang, et al.; Res. Square doi.org/10.21203/rs.3.rs-1697205/v1 ahead of print (2022)
- Membranes and deoxyribonucleic acid of hippocampal neurons damage due to low-density polyethylene microplastics in blood of Wistar rats: Y. Sincihu, et al.; Int. J. Health Sci. 6, 3490 (2022)
- Wistar Rats Hippocampal Neurons Response to Blood Low-Density Polyethylene Microplastics: A Pathway Analysis of SOD, CAT, MDA, 8-OHdG Expression in Hippocampal Neurons and Blood Serum Aβ42 Levels: Y. Sincihu, et al.; Neuropsych. Dis. Treat. 19, 73 (2023)