RevMab

anti-Symmetric Dimethyl-Histone H4 (Arg3), Rabbit Monoclonal (RM459)

CHF 251.00
In stock
REV-31-1351-00-C02525 µgCHF 251.00
REV-31-1351-00-C100100 µgCHF 559.00
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Product Details
Synonyms H4 R3me2
Product Type Recombinant Antibody
Properties
Clone RM459
Isotype Rabbit IgG
Source/Host Rabbit
Immunogen/Antigen A symmetric dimethyl-peptide corresponding to the symmetric demethylated Histone H4 (Arg3).
Application

Western Blot: 0.1 µg/ml - 2 µg/ml
Luminex: 0.001 µg/ml - 0.1 µg/ml

Crossreactivity Human
All Vertebrates
Specificity

This antibody reacts to Histone H4 symmetric dimethylated at arginine 3 (R3me2s). No cross-reactivity with unmodified arginine 3, monomethylated or asymmetric dimethylated arginine 3, or other methylated arginine in Histone H4 has been shown.

Purity Protein A purified.
Purity Detail Protein A affinity purified from an animal origin-free culture supernatant.
Concentration 1 mg/ml
Formulation Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Accession Number P62805
Declaration Manufactured by RevMab Biosciences.
Shipping and Handling
Shipping BLUE ICE
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

Histone H4 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H4 is involved with the structure of the nucleosome of the 'beads on a string' organization. Histone proteins are highly post-translationally modified. Covalently bonded modifications include acetylation and methylation of the N-terminal tails. These modifications may alter expression of genes located on DNA associated with its parent histone octamer. Histone H4 is an important protein in the structure and function of chromatin, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes.

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