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Product Details
Synonyms AMGTie2-1
Product Type Chemical
Formula C25H20F3N5O2
MW 479.5
CAS 870223-96-4
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO.
Declaration Manufactured by SynKinase.
Other Product Data Target: Tie-2 | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC(50) <1nM).
Product References
  1. Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor: B.L. Hodous, et al.; J. Med. Chem. 50, 611 (2007)
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