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SynKinase
AMG-Tie2-1
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| Product Details | |
|---|---|
| Synonyms | AMGTie2-1 |
| Product Type | Chemical |
| Properties | |
| Formula | C25H20F3N5O2 |
| MW | 479.5 |
| CAS | 870223-96-4 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: Tie-2 | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | ZVIWALRWYYSHSU-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC(50) <1nM).
Product References
- Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor: B.L. Hodous, et al.; J. Med. Chem. 50, 611 (2007)
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