Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
SynKinase
PIK-93
CHF 0.00
In stock
SYN-1066-M0011 mgCHF 149.00
SYN-1066-M0055 mgCHF 241.00
SYN-1066-M01010 mgCHF 369.00
SYN-1066-M05050 mgCHF 1'483.00
SYN-1066-M100100 mgINQ
Product Details | |
---|---|
Synonyms | PIK93 |
Product Type | Chemical |
Properties | |
Formula | C14H16ClN3O4S2 |
MW | 389.9 |
CAS | 593960-11-3 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | JFVNFXCESCXMBC-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
PIK-93 selectively inhibits the type III PI 4-kinase β enzyme (IC(50) of 19nM). It has also been shown to have activity on PI3Kα with an IC(50) of 39nM.
Product References
- Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha: E.R. Zunder, et al.; Cancer Cell 14, 180 (2008)