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SynKinase
PIK-93
CHF 0.00
In stock
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| Product Details | |
|---|---|
| Synonyms | PIK93 |
| Product Type | Chemical |
| Properties | |
| Formula | C14H16ClN3O4S2 |
| MW | 389.9 |
| CAS | 593960-11-3 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | JFVNFXCESCXMBC-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
PIK-93 selectively inhibits the type III PI 4-kinase β enzyme (IC(50) of 19nM). It has also been shown to have activity on PI3Kα with an IC(50) of 39nM.
Product References
- Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha: E.R. Zunder, et al.; Cancer Cell 14, 180 (2008)
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