SynKinase

PIK-93

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SYN-1066-M0011 mgCHF 149.00
SYN-1066-M0055 mgCHF 241.00
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SYN-1066-M100100 mgINQ
 
More Information
Product Details
Synonyms PIK93
Product Type Chemical
Properties
Formula C14H16ClN3O4S2
MW 389.9
CAS 593960-11-3
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key JFVNFXCESCXMBC-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
PIK-93 selectively inhibits the type III PI 4-kinase β enzyme (IC(50) of 19nM). It has also been shown to have activity on PI3Kα with an IC(50) of 39nM.
Product References
  1. Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha: E.R. Zunder, et al.; Cancer Cell 14, 180 (2008)
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