CHF 227.00
In stock
SYN-1106-M0011 mgCHF 227.00
SYN-1106-M0055 mgCHF 461.00
SYN-1106-M01010 mgCHF 724.00
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Product Details
Synonyms TG46
Product Type Chemical
Formula C26H34N6O3S
MW 510.7
CAS 936091-15-5
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: JAK | Kinase Group: PTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
TG-46 is an inhibitor of JAK2, FLT3, RET, JAK3 with IC(50) values of 6nM, 25nM, 17nM, 169nM respectively.
Product References
  1. TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations: A. Pardanani, et al.; Leukemia 21, 1658 (2007)
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