SYN-1191-M0011 mgCHF 270.00
SYN-1191-M0055 mgCHF 412.00
SYN-1191-M01010 mgCHF 702.00
|Solubility||Soluble in DMSO.|
|Declaration||Manufactured by SynKinase.|
|Other Product Data||
Target: PI3K - mTOR | Kinase Group: Lipid Kinase | Substrate: Lipid
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||+4°C|
|Use/Stability||Stable for at least 1 year after receipt when stored at +4°C.|
|Product Specification Sheet|
XL019 is a potent JAK2 inhibitor (IC(50) of 2nM) with excellent selectivity versus the other members of the JAK kinase family (JAK1, IC(50) of 130nM; JAK3, IC(50) of 250nM; TYK2, IC(50) of 340nM).
- SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors: T. Forsyth, et al.; Bioorg. Med. Chem. Lett. 22, 7653 (2012)